ea0098c9 | Clinical – Chemo/SSA/Biologics | NANETS2023
Sukrithan, MD Vineeth K.
, Ahmed Uzair
, Zhou Ye
, Rogers MD Kerry A.
, Konda, MD, MPH Bhavana
Background: The expression of BCL-2, an anti-apoptotic protein, has been implicated in the aggressive behavior of NENs. Dysregulation of BCL-2 expression, controlled by the pRb1-E2F1 axis, has been linked to the development of various cancers, including NENs. Studies have shown that higher BCL-2 expression is associated with poorer survival outcomes in NEN patients.Methods: We report a unique case of a patient with a pancreatic neuroendocrine tumor who h...